Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9119616 | 0.77 | HDAC8 (0.53) | NPC1RAB9ASMN1; SMN2MEN1MAPT | |
| SCHEMBL4113249 | 0.76 | KIF11 (0.47) | KIF11NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL4113245 | 0.76 | KIF11 (0.47) | KIF11NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL13756246 | 0.74 | MAPT (0.81) | KIF11NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL4983445 | 0.74 | NPC1 (0.53) | KIF11NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL2730172 | 0.74 | MAPT (0.81) | KIF11NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL31388334 | 0.74 | MAPT (0.55) | KIF11NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL8331892 | 0.73 | RAB9A (0.41) | KIF11NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL11184467 | 0.73 | TAS2R38 (0.50) | NPC1RAB9ASMN1; SMN2MEN1MAPT | |
| SCHEMBL2090688 | 0.72 | NPC1 (0.61) | KIF11NPC1RAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918460-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-06-02 | — | — | EP | disclosed |
| WO-1998004131-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1998-02-05 | — | — | WO | disclosed |