Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.81 |
| ▸ | NPC1 | O15118 | 3/20 | 0.81 |
| ▸ | RAB9A | P51151 | 3/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.81 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.81 |
| ▸ | HTT | P42858 | 2/20 | 0.81 |
| ▸ | MEN1 | O00255 | 1/20 | 0.81 |
| ▸ | XBP1 | P17861 | 1/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.81 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.79 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.79 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.76 |
| ▸ | KIF11 | P52732 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | STAT1 | P42224 | 1/20 | 0.63 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.61 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13756246 | 1.00 | MAPT (0.81) | MAPTNPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL17072026 | 0.92 | EPHX2 (0.74) | MAPTNPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL12585027 | 0.92 | MAPT (0.71) | MAPTNPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL10201044 | 0.90 | NPC1 (0.68) | MAPTNPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL22059470 | 0.89 | NR1H4 (1.00) | MAPTNPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL13141239 | 0.88 | NPC1 (0.68) | MAPTNPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL9037064 | 0.88 | NPC1 (0.66) | MAPTNPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL12264103 | 0.87 | RAB9A (0.65) | MAPTNPC1RAB9ASMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL9004709 | 0.86 | RAB9A (0.64) | MAPTNPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL22103804 | 0.86 | MAPT (0.63) | MAPTNPC1RAB9ASMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9290441-B2 | Use of ruthenium complexes for formation and/or hydrogenation of amides and related carboxylic acid derivatives | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2016-03-22 | — | — | US | claimed |
| US-20120253042-A1 | USE OF RUTHENIUM COMPLEXES FOR FORMATION AND/OR HYDROGENATION OF AMIDES AND RELATED CARBOXYLIC ACID DERIVATIVES | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2012-10-04 | — | — | US | claimed |
| US-12145139-B2 | Manganese based complexes and uses thereof for homogeneous catalysis | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2024-11-19 | — | — | US | disclosed |
| US-20230372915-A1 | MANGANESE BASED COMPLEXES AND USES THEREOF FOR HOMOGENEOUS CATALYSIS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2023-11-23 | — | — | US | disclosed |
| EP-3188832-B1 | RUTHENIUM COMPLEXES AND THEIR USES AS CATALYSTS IN PROCESSES FOR FORMATION AND/OR HYDROGENATION OF ESTERS, AMIDES AND RELATED REACTIONS | YEDA RES & DEV (IL) | 2023-10-04 | — | — | EP | disclosed |
| US-11731116-B2 | Manganese based complexes and uses thereof for homogeneous catalysis | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2023-08-22 | — | — | US | disclosed |
| CN-114213286-B | Synthetic method of urea derivative | 湖北文理学院 | 2022-12-30 | — | — | CN | disclosed |
| CN-110683969-B | Urea derivative and synthetic method thereof | 曲阜师范大学 | 2022-05-17 | — | — | CN | disclosed |
| EP-3919466-A1 | MANGANESE BASED COMPLEXES AND USES THEREOF FOR HOMOGENEOUS CATALYSIS | Yeda Research and Development Co. Ltd (IL) | 2021-12-08 | — | — | EP | disclosed |
| EP-2629889-B1 | RUTHENIUM COMPLEXES AND THEIR USES IN PROCESSES FOR FORMATION AND/OR HYDROGENATION OF ESTERS, AMIDES AND DERIVATIVES THEREOF | YEDA RES & DEV (IL) | 2019-04-03 | — | — | EP | disclosed |
| EP-2629889-B1 | RUTHENIUM COMPLEXES AND THEIR USES IN PROCESSES FOR FORMATION AND/OR HYDROGENATION OF ESTERS, AMIDES AND DERIVATIVES THEREOF | YEDA RES & DEV (IL) | 2019-04-03 | — | — | EP | disclosed |
| US-8952167-B2 | Pseudorotaxanes, rotaxanes and catenanes formed by metal ions templating | NATIONAL TAIWAN UNIVERSITY (TW) | 2015-02-10 | — | — | US | disclosed |
| US-8952167-B2 | Pseudorotaxanes, rotaxanes and catenanes formed by metal ions templating | NATIONAL TAIWAN UNIVERSITY (TW) | 2015-02-10 | — | — | US | disclosed |
| US-20140350242-A1 | PSEUDOROTAXANES, ROTAXANES AND CATENANES FORMED BY METAL IONS TEMPLATING | NATIONAL TAIWAN UNIVERSITY (TW) | 2014-11-27 | — | — | US | disclosed |
| US-20140350242-A1 | PSEUDOROTAXANES, ROTAXANES AND CATENANES FORMED BY METAL IONS TEMPLATING | NATIONAL TAIWAN UNIVERSITY (TW) | 2014-11-27 | — | — | US | disclosed |
| US-20130281664-A1 | NOVEL RUTHENIUM COMPLEXES AND THEIR USES IN PROCESSES FOR FORMATION AND/OR HYDROGENATION OF ESTERS, AMIDES AND DERIVATIVES THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2013-10-24 | — | — | US | disclosed |
| US-20130281664-A1 | NOVEL RUTHENIUM COMPLEXES AND THEIR USES IN PROCESSES FOR FORMATION AND/OR HYDROGENATION OF ESTERS, AMIDES AND DERIVATIVES THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2013-10-24 | — | — | US | disclosed |
| EP-2629889-A2 | NOVEL RUTHENIUM COMPLEXES AND THEIR USES IN PROCESSES FOR FORMATION AND/OR HYDROGENATION OF ESTERS, AMIDES AND DERIVATIVES THEREOF | Yeda Research and Development Co. Ltd. (IL) | 2013-08-28 | — | — | EP | disclosed |
| US-20120253042-A1 | USE OF RUTHENIUM COMPLEXES FOR FORMATION AND/OR HYDROGENATION OF AMIDES AND RELATED CARBOXYLIC ACID DERIVATIVES | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2012-10-04 | — | — | US | disclosed |
| WO-2012052996-A2 | NOVEL RUTHENIUM COMPLEXES AND THEIR USES IN PROCESSES FOR FORMATION AND/OR HYDROGENATION OF ESTERS, AMIDES AND DERIVATIVES THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2012-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230372915-A1 | MANGANESE BASED COMPLEXES AND USES THEREOF FOR HOMOGENEOUS CATALYSIS | ADH1C, OTC, MLEC | MAPT 3761/4885NPC1 3936/4885RAB9A 3933/4885 |
| US-20120253042-A1 | USE OF RUTHENIUM COMPLEXES FOR FORMATION AND/OR HYDROGENATION OF AMIDES AND RELATED CARBOXYLIC ACID DERIVATIVES | ADH5, ADH1C, ADH1A | MAPT 3690/4885NPC1 4444/4885RAB9A 3469/4885 |
| US-12145139-B2 | Manganese based complexes and uses thereof for homogeneous catalysis | ADH1C, OTC, MLEC | MAPT 3761/4885NPC1 3936/4885RAB9A 3933/4885 |
| US-20140350242-A1 | PSEUDOROTAXANES, ROTAXANES AND CATENANES FORMED BY METAL IONS TEMPLATING | PCNA, TIMCC, SGTA | MAPT 642/4885NPC1 4843/4885RAB9A 3133/4885 |
| US-20130281664-A1 | NOVEL RUTHENIUM COMPLEXES AND THEIR USES IN PROCESSES FOR FORMATION AND/OR HYDROGENATION OF ESTERS, AMIDES AND DERIVATIVES THEREOF | ADH5, ADH1C, ADH1A | MAPT 3645/4885NPC1 4697/4885RAB9A 3970/4885 |
| US-11731116-B2 | Manganese based complexes and uses thereof for homogeneous catalysis | ADH1C, OTC, ADH5 | MAPT 3901/4885NPC1 3865/4885RAB9A 3981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.