Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 3/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8398724 | 0.89 | NISCH (0.38) | NISCHL3MBTL1KMT2AMEN1LMNA | |
| SCHEMBL8400227 | 0.87 | NISCH (0.37) | NISCHL3MBTL1KMT2AMEN1FABP4 | |
| SCHEMBL8395408 | 0.86 | CYP3A4 (0.43) | KMT2AMEN1LMNACYP3A4RECQL | |
| SCHEMBL8399060 | 0.85 | TP53 (0.45) | L3MBTL1KMT2AMEN1FABP4FABP5 | |
| SCHEMBL8399129 | 0.85 | LMNA (0.41) | L3MBTL1KMT2AMEN1LMNACYP3A4 | |
| SCHEMBL8396234 | 0.85 | PPARD (0.39) | NISCHLMNACYP3A4SNCAHIF1A | |
| SCHEMBL8399072 | 0.83 | THRA (0.41) | LMNACYP3A4SNCACYP1A2CYP2C19 | |
| SCHEMBL8395164 | 0.83 | CYP3A4 (0.41) | L3MBTL1KMT2AMEN1LMNACYP3A4 | |
| SCHEMBL8399032 | 0.82 | THRA (0.45) | KMT2AMEN1CYP3A4PPARGCYP1A2 | |
| SCHEMBL8397821 | 0.82 | RXRA (0.41) | LMNARXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644183-B1 | Process of producing N-alkylacetamides | SHIONOGI & CO (JP) | 1999-06-02 | — | — | EP | disclosed |
| US-5498792-A | Process of producing N-alkylacetamides | SHIONOGI & CO., LTD. (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0644183-A2 | Process of producing N-alkylacetamides | SHIONOGI & CO., LTD. (JP) | 1995-03-22 | — | — | EP | disclosed |