Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | RARA | P10276 | 4/20 | 0.30 |
| ▸ | RARB | P10826 | 4/20 | 0.30 |
| ▸ | RARG | P13631 | 4/20 | 0.30 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8399426 | 0.76 | MAPT (0.31) | — | |
| SCHEMBL7620903 | 0.76 | MCL1 (0.36) | ALDH1A1MCL1KDM4EMEN1KMT2A | |
| SCHEMBL7841595 | 0.64 | KDM4E (0.36) | ALDH1A1KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL30218698 | 0.63 | ALDH1A1 (0.47) | ALDH1A1KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL18936275 | 0.63 | ALDH1A1 (0.47) | ALDH1A1KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL28650743 | 0.63 | ALDH1A1 (0.46) | ALDH1A1MCL1KDM4EMEN1KMT2A | |
| SCHEMBL6721499 | 0.63 | NOTUM (0.33) | ALDH1A1KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL6726207 | 0.63 | RXRA (0.35) | KDM4EMEN1KMT2ATDP1RARA | |
| SCHEMBL6977102 | 0.63 | MCL1 (0.31) | MCL1 | |
| SCHEMBL7620950 | 0.63 | ALDH1A1 (0.40) | ALDH1A1KDM4EMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5885936-A | BENZOTHIOPYRAN DERIVATIVES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-03-23 | — | — | US | disclosed |
| EP-0860441-A1 | Herbicidal derivatives of 1,4-dithiino(2,3c)benzothiopyran | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-08-26 | — | — | EP | disclosed |