Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 10/20 | 0.35 |
| ▸ | RARA | P10276 | 8/20 | 0.35 |
| ▸ | RARB | P10826 | 7/20 | 0.35 |
| ▸ | RARG | P13631 | 7/20 | 0.35 |
| ▸ | RXRG | P48443 | 6/20 | 0.35 |
| ▸ | RXRB | P28702 | 5/20 | 0.35 |
| ▸ | HNF4A | P41235 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6721524 | 0.86 | RXRA (0.35) | RXRARARARARBRARGRXRG | |
| SCHEMBL9036741 | 0.86 | RARA (0.34) | RXRARARARARBRARGRXRG | |
| SCHEMBL6721464 | 0.85 | KDM4E (0.35) | RXRARARARARBRARGRXRG | |
| SCHEMBL8346248 | 0.83 | HPGD (0.33) | MEN1KMT2AKDM4ETDP1NOTUM | |
| SCHEMBL8344681 | 0.81 | RXRA (0.30) | RXRARXRGRXRB | |
| SCHEMBL7828888 | 0.81 | RXRA (0.35) | RXRARARARARBRARGRXRG | |
| SCHEMBL6725577 | 0.77 | RARA (0.32) | RXRARARARARBRARGPTGS1 | |
| SCHEMBL8647409 | 0.76 | ALDH1A1 (0.31) | — | |
| SCHEMBL6733149 | 0.75 | — | — | |
| SCHEMBL7839850 | 0.75 | RARA (0.41) | RXRARARARARBRARGRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677460-B1 | Aromatic carboxylic acid bicyclic sulfur compounds | IDEMITSU KOSAN COMPANY, LIMITED (JP) | 2004-01-13 | — | — | US | disclosed |
| US-20030236421-A1 | AROMATIC CARBOXYLIC ACID BICYCLIC SULFUR COMPOUNDS | IDEMITSU KOSAN COMPANY, LIMITED (JP) | 2003-12-25 | — | — | US | disclosed |
| US-20020133024-A1 | Aromatic carboxylic acid bicyclic sulfur compounds | IDEMITSU KOSAN COMPANY, LIMITED (JP) | 2002-09-19 | — | — | US | disclosed |
| US-20010051733-A1 | Aromatic carboxylic acid bicyclic sulfur compounds | IDEMITSU KOSAN COMPANY, LIMITED (JP) | 2001-12-13 | — | — | US | disclosed |
| EP-0712853-B1 | PYRAZOLE DERIVATIVE | IDEMITSU KOSAN CO (JP) | 2001-02-28 | — | — | EP | disclosed |
| US-6136755-A | HERBICIDES | IDEMITSU KOSAN CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| US-6103668-A | Pyrazole derivatives | IDEMITSU KOSAN CO., LTD. (JP) | 2000-08-15 | — | — | US | disclosed |
| US-6063936-A | CARBOXY SUBSTITUTED BENZOTHIOPHENES USED AS HERBICIDE | IDEMITSU KOSAN CO., LTD. (JP) | 2000-05-16 | — | — | US | disclosed |
| US-5767289-A | HERBICIDE INTERMEDIATES | IDEMITSU KOSAN COMPANY, LIMITED (JP) | 1998-06-16 | — | — | US | disclosed |
| EP-0810227-A1 | ISOXAZOLE DERIVATIVES | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1997-12-03 | — | — | EP | disclosed |
| US-5607898-A | HERBICIDES | IDEMITSU KOSAN COMPANY, LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| EP-0712853-A1 | PYRAZOLE DERIVATIVE | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1996-05-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236421-A1 | AROMATIC CARBOXYLIC ACID BICYCLIC SULFUR COMPOUNDS | XDH, SULT2A1, NAT1 | RXRA 426/4885RARA 2231/4885RARB 2546/4885 |
| US-20010051733-A1 | Aromatic carboxylic acid bicyclic sulfur compounds | XDH, SULT2A1, NAT1 | RXRA 426/4885RARA 2231/4885RARB 2546/4885 |
| US-20020133024-A1 | Aromatic carboxylic acid bicyclic sulfur compounds | XDH, SULT2A1, NAT1 | RXRA 426/4885RARA 2231/4885RARB 2546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.