Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 6/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.31 |
| ▸ | LDHA | P00338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8395489 | 0.83 | AKR1B1 (0.39) | MEN1KMT2AHTTSMN1; SMN2AKR1B1 | |
| SCHEMBL8395540 | 0.83 | LDHA (0.31) | MEN1KMT2AHTTSMN1; SMN2HIF1A | |
| SCHEMBL8397057 | 0.82 | AKR1B1 (0.39) | AKR1B1 | |
| SCHEMBL8399269 | 0.82 | MAPT (0.38) | SMN1; SMN2AKR1B1NPC1L3MBTL1 | |
| SCHEMBL8399262 | 0.82 | AKR1B1 (0.40) | MEN1KMT2AHTTSMN1; SMN2AKR1B1 | |
| SCHEMBL8400483 | 0.80 | AKR1B1 (0.44) | MEN1KMT2ASMN1; SMN2AKR1B1NPC1 | |
| SCHEMBL8395435 | 0.80 | AKR1B1 (0.38) | MEN1KMT2AHTTSMN1; SMN2AKR1B1 | |
| SCHEMBL8399351 | 0.80 | AKR1B1 (0.46) | SMN1; SMN2AKR1B1NPC1TRPM5 | |
| SCHEMBL8396655 | 0.79 | HDAC6 (0.50) | MEN1KMT2ASMN1; SMN2AKR1B1NPC1 | |
| SCHEMBL8400189 | 0.76 | AKR1B1 (0.36) | AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |