Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.37 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8395489 | 0.91 | AKR1B1 (0.39) | AKR1B1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8400483 | 0.87 | AKR1B1 (0.44) | AKR1B1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8395435 | 0.87 | AKR1B1 (0.38) | AKR1B1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8399351 | 0.86 | AKR1B1 (0.46) | AKR1B1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8396655 | 0.86 | HDAC6 (0.50) | AKR1B1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8399269 | 0.82 | MAPT (0.38) | AKR1B1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8399274 | 0.82 | MEN1 (0.34) | AKR1B1SMN1; SMN2NPC1L3MBTL1HTT | |
| SCHEMBL8399113 | 0.82 | NOS1 (0.44) | AKR1B1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8399195 | 0.80 | MAPT (0.39) | MAPTAURKAABL1NTRK1LCK | |
| SCHEMBL8396268 | 0.80 | AKR1B1 (0.41) | AKR1B1MAPTSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |