Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PLEC | Q15149 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8400483 | 0.91 | AKR1B1 (0.44) | AKR1B1NPC1RAB9ATRPM5ALDH1A1 | |
| SCHEMBL8395435 | 0.91 | AKR1B1 (0.38) | AKR1B1NPC1RAB9ATRPM5ALDH1A1 | |
| SCHEMBL8399262 | 0.91 | AKR1B1 (0.40) | AKR1B1NPC1RAB9ATRPM5ALDH1A1 | |
| SCHEMBL8399351 | 0.90 | AKR1B1 (0.46) | AKR1B1NPC1RAB9ATRPM5MAPT | |
| SCHEMBL8396655 | 0.87 | HDAC6 (0.50) | AKR1B1NPC1RAB9ATRPM5ALDH1A1 | |
| SCHEMBL8399113 | 0.85 | NOS1 (0.44) | AKR1B1NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL8399269 | 0.83 | MAPT (0.38) | AKR1B1NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL8399274 | 0.83 | MEN1 (0.34) | AKR1B1NPC1TRPM5MEN1KMT2A | |
| SCHEMBL8399092 | 0.82 | AKR1B1 (0.38) | AKR1B1 | |
| SCHEMBL8399732 | 0.82 | AKR1B1 (0.42) | AKR1B1RAB9ATRPM5ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |