Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 2/20 | 0.33 |
| ▸ | ACE | P12821 | 2/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8403464 | 0.90 | ACE (0.34) | KDM4EALOX15TSHRSIRT1MAPT | |
| SCHEMBL8398839 | 0.67 | PARP1 (0.41) | KDM4EALOX15TSHRSIRT1MAPT | |
| SCHEMBL8402362 | 0.66 | PARP1 (0.40) | ITGB3ITGA2BALDH1A1 | |
| SCHEMBL6678145 | 0.66 | ITGB3 (0.43) | ITGB3ITGA2B | |
| SCHEMBL8399640 | 0.65 | ITGB3 (0.45) | ITGB3ITGA2B | |
| SCHEMBL7595704 | 0.63 | ITGB3 (0.54) | MAPTITGB3ITGA2B | |
| SCHEMBL8399643 | 0.63 | ITGB3 (0.41) | KDM4EALOX15TSHRSIRT1MAPT | |
| SCHEMBL7444076 | 0.62 | ITGB3 (0.48) | ITGB3ITGA2BALDH1A1 | |
| SCHEMBL7396984 | 0.62 | ITGB3 (0.75) | KDM4EITGB3ITGA2BALDH1A1 | |
| SCHEMBL315339 | 0.62 | KDM4E (1.00) | KDM4EALOX15TSHRSIRT1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939412-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-17 | — | — | US | disclosed |
| US-5693636-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-02 | — | — | US | disclosed |