Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8403244 | 0.80 | NPSR1 (0.50) | ALDH1A1LMNANPSR1ALOX15HTT | |
| SCHEMBL5312235 | 0.74 | NPC1 (0.42) | ALDH1A1LMNAKMT2AF2CES2 | |
| SCHEMBL8403591 | 0.74 | CA2 (0.44) | ALDH1A1KMT2A | |
| SCHEMBL11375273 | 0.70 | LMNA (0.52) | ALDH1A1LMNANPSR1ALOX15HTT | |
| SCHEMBL27846222 | 0.70 | KMT2A (0.60) | ALDH1A1LMNANPSR1HTTKMT2A | |
| SCHEMBL3469060 | 0.70 | VNN1 (0.63) | ALDH1A1LMNANPSR1ALOX15KMT2A | |
| SCHEMBL15198839 | 0.69 | ALDH1A1 (0.43) | ALDH1A1NPSR1HTTKMT2ARAB9A | |
| SCHEMBL15100717 | 0.69 | LMNA (0.55) | ALDH1A1LMNANPSR1ALOX15HTT | |
| SCHEMBL10877250 | 0.68 | ALDH1A1 (0.49) | ALDH1A1LMNANPSR1ALOX15HTT | |
| SCHEMBL51509 | 0.68 | RXFP1 (0.79) | ALDH1A1LMNANPSR1KMT2ACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952368-A | AN INHIBITORS OF PROSTAGLANDIN G/H SYNTHASE, ANTIINFLAMMATORY AND ANALGESIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1999-09-14 | — | — | US | disclosed |