Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CDC25A | P30304 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.34 |
| ▸ | ITGAV | P06756 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8401206 | 0.82 | NR1H2 (0.38) | GAACDC25ALMNATSHRMGLL | |
| SCHEMBL8398953 | 0.74 | ITGB3 (0.42) | GAAITGB3ITGAVKDM4EALDH1A1 | |
| SCHEMBL5800676 | 0.72 | GAA (0.49) | GAACDC25AITGB3ITGAVMAPT | |
| SCHEMBL4431229 | 0.72 | GAA (0.49) | GAACDC25AITGB3ITGAVMAPT | |
| SCHEMBL6879503 | 0.68 | CYP1A2 (0.47) | GAACDC25ATSHRITGB3ITGAV | |
| SCHEMBL9055178 | 0.65 | GAA (0.75) | GAALMNAITGB3ITGAVMAPT | |
| SCHEMBL8503077 | 0.64 | ITGB3 (0.61) | ITGB3ITGAV | |
| SCHEMBL8402405 | 0.63 | CASP3 (0.44) | GAALMNATSHRITGB3MAPT | |
| SCHEMBL4421212 | 0.62 | CYP1A2 (0.51) | GAATSHRMAPTMEN1KMT2A | |
| SCHEMBL4420851 | 0.61 | ALDH1A1 (0.74) | GAALMNATSHRMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693636-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-02 | — | — | US | claimed |
| US-5939412-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-17 | — | — | US | disclosed |
| US-5693636-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-02 | — | — | US | disclosed |