Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | PARK7 | Q99497 | 3/20 | 0.34 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.34 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGAV | P06756 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8398963 | 0.72 | ALDH1A1 (0.35) | ALDH1A1PARK7ALDH2ALDH3A1KDM4E | |
| SCHEMBL8402364 | 0.71 | ALDH1A1 (0.38) | ALDH1A1PARK7ALDH2ALDH3A1KDM4E | |
| SCHEMBL8402425 | 0.65 | ALDH1A1 (0.34) | ALDH1A1PARK7ALDH2ALDH3A1KDM4E | |
| SCHEMBL8519054 | 0.62 | ALDH1A1 (0.33) | ALDH1A1PARK7ALDH2ALDH3A1KDM4E | |
| SCHEMBL8897087 | 0.62 | ALDH1A1 (0.35) | ALDH1A1PARK7ALDH2ALDH3A1KDM4E | |
| SCHEMBL2823268 | 0.59 | ALDH1A1 (0.66) | ALDH1A1PARK7ALDH2ALDH3A1KDM4E | |
| SCHEMBL1200625 | 0.56 | KMT2A (0.72) | ALDH1A1HPGDSMN1; SMN2KMT2A | |
| SCHEMBL3931444 | 0.56 | CASP3 (0.61) | ALDH1A1PARK7ALDH2ALDH3A1KDM4E | |
| SCHEMBL8402405 | 0.56 | CASP3 (0.44) | ALDH1A1PARK7ALDH2ALDH3A1KDM4E | |
| SCHEMBL12930286 | 0.56 | CDC25A (0.67) | ALDH1A1PARK7ALDH2ALDH3A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939412-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-17 | — | — | US | disclosed |