Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PARK7 | Q99497 | 2/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.33 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 5/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8398963 | 0.90 | ALDH1A1 (0.35) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8519716 | 0.89 | ALDH1A1 (0.36) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8898521 | 0.82 | ALDH1A1 (0.35) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8401267 | 0.74 | ALDH1A1 (0.38) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8402364 | 0.74 | ALDH1A1 (0.38) | ALDH1A1MAPTSMN1; SMN2KMT2AHSD17B10 | |
| SCHEMBL8897079 | 0.70 | PARP1 (0.39) | ALDH1A1MAPTUSP2ALOX15MAPK1 | |
| SCHEMBL8401282 | 0.68 | ALDH1A1 (0.37) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8402425 | 0.66 | ALDH1A1 (0.34) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8898197 | 0.64 | CCKBR (0.35) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8519054 | 0.63 | ALDH1A1 (0.33) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693636-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-02 | — | — | US | disclosed |