Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | PARK7 | Q99497 | 4/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 3/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8398963 | 0.84 | ALDH1A1 (0.35) | ALDH1A1PARK7ALDH2ALDH3A1MAPT | |
| SCHEMBL8897087 | 0.74 | ALDH1A1 (0.35) | ALDH1A1PARK7ALDH2ALDH3A1MAPT | |
| SCHEMBL8402425 | 0.72 | ALDH1A1 (0.34) | ALDH1A1PARK7ALDH2ALDH3A1MAPT | |
| SCHEMBL8401296 | 0.71 | ALDH1A1 (0.34) | ALDH1A1PARK7ALDH2ALDH3A1MAPT | |
| SCHEMBL8519716 | 0.70 | ALDH1A1 (0.36) | ALDH1A1PARK7ALDH2ALDH3A1MAPT | |
| SCHEMBL8401353 | 0.69 | CCKBR (0.32) | ALDH1A1PARK7ALDH2ALDH3A1MAPT | |
| SCHEMBL8519054 | 0.67 | ALDH1A1 (0.33) | ALDH1A1PARK7ALDH2ALDH3A1MAPT | |
| SCHEMBL8898521 | 0.67 | ALDH1A1 (0.35) | ALDH1A1PARK7ALDH2ALDH3A1MAPT | |
| Hydrochloric Acid SCHEMBL6701567 | 0.64 | ATM (0.37) | ALDH1A1CA9CA12MDM2KMT2A | |
| SCHEMBL8402362 | 0.63 | PARP1 (0.40) | ALDH1A1PARK7CACNA1GCACNA1HCACNA1I |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939412-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-17 | — | — | US | disclosed |
| US-5693636-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-02 | — | — | US | disclosed |