Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.30 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.30 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8402425 | 0.82 | ALDH1A1 (0.34) | ALDH1A1MAPTRAB9AKDM4EGAA | |
| SCHEMBL8401353 | 0.76 | CCKBR (0.32) | ALDH1A1MAPTRAB9AKDM4EGAA | |
| SCHEMBL8398963 | 0.73 | ALDH1A1 (0.35) | ALDH1A1MAPTRAB9AKDM4EGAA | |
| SCHEMBL8402364 | 0.67 | ALDH1A1 (0.38) | ALDH1A1MAPTRAB9AKDM4EGAA | |
| SCHEMBL8898197 | 0.66 | CCKBR (0.35) | ALDH1A1MAPTRAB9AGAASMN1; SMN2 | |
| SCHEMBL8398754 | 0.64 | S1PR1 (0.32) | — | |
| SCHEMBL8897087 | 0.63 | ALDH1A1 (0.35) | ALDH1A1MAPTRAB9AKDM4EGAA | |
| SCHEMBL8401296 | 0.62 | ALDH1A1 (0.34) | ALDH1A1MAPTRAB9AKDM4EGAA | |
| SCHEMBL8519716 | 0.60 | ALDH1A1 (0.36) | ALDH1A1MAPTRAB9AKDM4EGAA | |
| SCHEMBL8898521 | 0.59 | ALDH1A1 (0.35) | ALDH1A1MAPTRAB9AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693636-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-02 | — | — | US | claimed |
| US-5939412-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-17 | — | — | US | disclosed |
| US-5693636-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-02 | — | — | US | disclosed |