Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | BMP1 | P13497 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8400807 | 0.87 | ALDH1A1 (0.53) | ALDH1A1HSD17B10TSHRPOLBPKM | |
| SCHEMBL8406398 | 0.84 | ALDH1A1 (0.51) | ALDH1A1HSD17B10TSHRPOLBPKM | |
| SCHEMBL8403382 | 0.81 | MMP9 (0.45) | MMP1MMP2MMP3BMP1MEP1B | |
| SCHEMBL8404841 | 0.80 | BMP1 (0.43) | MMP1MMP2MMP3BMP1MEP1B | |
| SCHEMBL8013077 | 0.80 | BMP1 (0.55) | ALDH1A1TSHRPOLBPKMMMP1 | |
| SCHEMBL8012143 | 0.80 | MMP2 (0.54) | ALDH1A1HSD17B10TSHRPOLBPKM | |
| SCHEMBL8400820 | 0.80 | ALDH1A1 (0.49) | ALDH1A1HSD17B10TSHRPOLBPKM | |
| SCHEMBL8403388 | 0.80 | TSHR (0.55) | ALDH1A1HSD17B10TSHRPOLBPKM | |
| SCHEMBL8405651 | 0.80 | ALDH1A1 (0.49) | ALDH1A1HSD17B10TSHRPOLBPKM | |
| SCHEMBL8015007 | 0.79 | BMP1 (0.52) | ALDH1A1HSD17B10TSHRPOLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0922030-A1 | ARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | PFIZER INC. (US) | 1999-06-16 | — | — | EP | disclosed |
| WO-1998007697-A1 | ARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | PFIZER INC. (US) | 1998-02-26 | — | — | WO | disclosed |