SCHEMBL8404841

SCHEMBL8404841

CCOC(=O)C1CN(C(=O)CCN(CC(C)CC(=O)NO)S(=O)(=O)c2ccc(OC)cc2)CCN1

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
BMP1 P13497 11/20 0.43
MEP1B Q16820 1/20 0.43
MMP1 P03956 6/20 0.41
MMP7 P09237 3/20 0.41
MMP13 P45452 3/20 0.41
MMP8 P22894 3/20 0.41
MMP12 P39900 2/20 0.41
MMP3 P08254 6/20 0.41
MMP2 P08253 2/20 0.41
MMP9 P14780 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8012844 0.84 MMP2 (0.50) BMP1MMP1MMP13MMP8MMP2
SCHEMBL8401078 0.81 BMP1 (0.47) BMP1MEP1BMMP1MMP7MMP13
SCHEMBL8404013 0.80 ALDH1A1 (0.51) BMP1MEP1BMMP1MMP8MMP3
SCHEMBL8400807 0.72 ALDH1A1 (0.53) BMP1MEP1B
SCHEMBL8403382 0.71 MMP9 (0.45) BMP1MEP1BMMP1MMP7MMP13
SCHEMBL8406398 0.71 ALDH1A1 (0.51) BMP1MEP1BMMP3
SCHEMBL8403388 0.70 TSHR (0.55) BMP1MMP1MMP8
SCHEMBL8400820 0.70 ALDH1A1 (0.49) BMP1MMP1MMP8
SCHEMBL8405651 0.70 ALDH1A1 (0.49) BMP1MMP1MMP13MMP8MMP3
SCHEMBL8403426 0.69 TSHR (0.48) BMP1MMP1MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0922030-A1 ARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES PFIZER INC. (US) 1999-06-16 EP claimed
WO-1998007697-A1 ARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES PFIZER INC. (US) 1998-02-26 WO claimed