Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.73 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.73 |
| ▸ | TSHR | P16473 | 1/20 | 0.73 |
| ▸ | ACHE | P22303 | 1/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.73 |
| ▸ | BLM | P54132 | 2/20 | 0.71 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.71 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | SCN1A | P35498 | 1/20 | 0.59 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.59 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12845484 | 0.88 | LMNA (0.72) | ALDH1A1LMNASLC22A2SLC22A1TSHR | |
| SCHEMBL19634734 | 0.86 | ALDH1A1 (0.58) | ALDH1A1LMNASLC22A2SLC22A1TSHR | |
| SCHEMBL8404683 | 0.85 | LMNA (0.52) | ALDH1A1LMNASLC22A2SLC22A1TSHR | |
| SCHEMBL5009757 | 0.84 | ALDH1A1 (0.60) | ALDH1A1LMNASLC22A2SLC22A1TSHR | |
| SCHEMBL3629060 | 0.84 | ALDH1A1 (0.77) | ALDH1A1LMNASLC22A2SLC22A1TSHR | |
| Procainamide SCHEMBL15914 | 0.84 | ALDH1A1 (1.00) | ALDH1A1LMNASLC22A2SLC22A1TSHR | |
| Procainamide SCHEMBL28944214 | 0.83 | ALDH1A1 (0.97) | ALDH1A1LMNASLC22A2SLC22A1TSHR | |
| Procainamide SCHEMBL9614531 | 0.83 | BLM (1.00) | ALDH1A1LMNASLC22A2SLC22A1TSHR | |
| Procainamide SCHEMBL40758 | 0.83 | BLM (1.00) | ALDH1A1LMNASLC22A2SLC22A1TSHR | |
| SCHEMBL9254351 | 0.83 | ALDH1A1 (0.74) | ALDH1A1LMNASLC22A2SLC22A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3213056-B1 | METHODS FOR THE RAPID PREPARATION OF LABELED GLYCOSYLAMINES AND FOR THE ANALYSIS OF GLYCOSYLATED BIOMOLECULES PRODUCING THE SAME | WATERS TECHNOLOGIES CORP (US) | 2020-08-12 | — | — | EP | disclosed |
| WO-2017200984-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2017-11-23 | — | — | WO | disclosed |