Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7569714 | 0.85 | ALDH1A1 (0.45) | MEN1LMNAPOLBKMT2ANOTUM | |
| SCHEMBL8399931 | 0.82 | NPC1 (0.48) | MEN1LMNAPOLBKMT2ANOTUM | |
| SCHEMBL7564976 | 0.73 | ALDH1A1 (0.61) | MEN1LMNAPOLBKMT2ANOTUM | |
| SCHEMBL25914397 | 0.70 | HDAC6 (0.48) | MEN1LMNAPOLBKMT2ANOTUM | |
| SCHEMBL1202589 | 0.69 | RECQL (0.46) | LMNAPOLBKMT2AALDH1A1CA2 | |
| SCHEMBL20409773 | 0.69 | NPC1 (0.71) | MEN1LMNAKMT2ANOTUMACHE | |
| SCHEMBL25914392 | 0.69 | NOTUM (0.65) | MEN1LMNAPOLBKMT2ANOTUM | |
| SCHEMBL1272321 | 0.68 | NOTUM (0.58) | MEN1LMNAPOLBKMT2ANOTUM | |
| SCHEMBL5334470 | 0.68 | ACHE (0.56) | LMNANOTUMACHEBCHENPC1 | |
| SCHEMBL7562885 | 0.68 | CHUK (0.39) | NOTUMACHEBCHENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842163-B1 | BENZENE DERIVATIVES WITH A HETEROCYCLIC GROUP | BASF AG (DE) | 1999-11-03 | — | — | EP | disclosed |
| US-5886187-A | Benzene derivatives having a heterocyclic radical | BASF AKTIENGESELLSCHAFT (DE) | 1999-03-23 | — | — | US | disclosed |