Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6848455 | 0.89 | CA2 (0.38) | TAAR1MAOBIDO1L3MBTL1HTR3A | |
| SCHEMBL5488470 | 0.86 | TAAR1 (0.48) | TAAR1MAOBIDO1AOC3L3MBTL1 | |
| SCHEMBL5482832 | 0.84 | IGF1R (0.50) | TAAR1MAOBIDO1AOC3L3MBTL1 | |
| SCHEMBL926567 | 0.80 | CA2 (0.37) | TAAR1L3MBTL1 | |
| SCHEMBL27812323 | 0.78 | ESR1 (0.59) | TAAR1L3MBTL1HTR3AIGF1RALOX15 | |
| SCHEMBL5488977 | 0.78 | TAAR1 (0.50) | TAAR1IDO1CYP2A6CNR1 | |
| SCHEMBL840528 | 0.78 | CYP1A2 (0.50) | TAAR1IDO1IGF1RALOX15CYP1A2 | |
| SCHEMBL1579879 | 0.78 | TRPA1 (0.40) | TAAR1 | |
| SCHEMBL2135113 | 0.78 | TAAR1 (0.68) | TAAR1MAOBIDO1AOC3HTR3E | |
| SCHEMBL208903 | 0.77 | TDP1 (0.52) | TAAR1MAOBIDO1AOC3ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |