Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2496116 | 0.81 | PIN1 (0.47) | PDE5AL3MBTL1ALDH1A1PIN1CYP1A2 | |
| SCHEMBL9698267 | 0.80 | KMT2A (0.49) | KMT2AL3MBTL1MEN1ALDH1A1NPC1 | |
| SCHEMBL12423709 | 0.79 | PIN1 (0.59) | PDE5AL3MBTL1ALDH1A1KDM4EPIN1 | |
| SCHEMBL30683113 | 0.79 | PIN1 (0.59) | PDE5AL3MBTL1ALDH1A1KDM4EPIN1 | |
| SCHEMBL669089 | 0.79 | MGMT (0.52) | L3MBTL1NFKB1PIN1CYP1A2CYP2C9 | |
| SCHEMBL14973934 | 0.73 | GABRA5 (0.48) | PDE5AKMT2AL3MBTL1SQORMEN1 | |
| SCHEMBL28646599 | 0.73 | RAB9A (0.52) | PDE5AKMT2AL3MBTL1MEN1NPC1 | |
| SCHEMBL15614406 | 0.72 | L3MBTL1 (0.46) | PDE5AL3MBTL1SQORALDH1A1NFKB1 | |
| SCHEMBL847077 | 0.72 | LMNA (0.47) | PDE5AL3MBTL1ALDH1A1PIN1CYP1A2 | |
| SCHEMBL8509535 | 0.72 | L3MBTL1 (0.46) | PDE5AL3MBTL1GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919930-A | Process for cross-coupling aromatic boron compounds with aromatic halogen compounds or perfluoroalkylsulfonates | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-07-06 | — | — | US | disclosed |