Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CAPNS1 | P04632 | 1/20 | 0.36 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810086 | 0.91 | CA2 (0.47) | MMP2MMP1MMP3MMP7MMP9 | |
| SCHEMBL8404245 | 0.91 | CAPN1 (0.42) | CAPN1CA1CA2CA7CA4 | |
| SCHEMBL8808434 | 0.91 | MMP2 (0.37) | MMP2MMP1MMP3MMP7MMP9 | |
| SCHEMBL8403868 | 0.90 | MMP13 (0.45) | MMP2MMP1MMP3MMP7MMP9 | |
| SCHEMBL8404228 | 0.85 | CAPN1 (0.43) | CAPN1MEN1KMT2ALMNACAPNS1 | |
| SCHEMBL8407770 | 0.84 | CAPN1 (0.48) | MMP2MMP1MMP3MMP7MMP9 | |
| SCHEMBL8406511 | 0.84 | CAPN1 (0.49) | MMP2MMP1MMP3MMP7MMP9 | |
| SCHEMBL8406503 | 0.84 | CAPN1 (0.49) | MMP2MMP1MMP3MMP7MMP9 | |
| SCHEMBL8808273 | 0.84 | SLC1A3 (0.39) | CAPN1CA1CA2CA7CAPNS1 | |
| SCHEMBL8406506 | 0.83 | CA1 (0.39) | MMP2MMP1MMP3MMP7MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925786-A1 | REMEDIES FOR ISCHEMIC DISEASES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1999-06-30 | — | — | EP | disclosed |