Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PHGDH | O43175 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8061708 | 0.95 | TTR (0.41) | TTRSMN1; SMN2NPC1RAB9AHDAC1 | |
| SCHEMBL8406942 | 0.93 | MAP3K7 (0.39) | TTREPHX2LMNAMEN1KMT2A | |
| SCHEMBL8409160 | 0.91 | TTR (0.40) | TTRMAPK8SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8043973 | 0.89 | HTT (0.40) | TTRNPC1RAB9AEPHX2POLB | |
| SCHEMBL8408952 | 0.86 | NPC1 (0.47) | TTRMAPK8SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8055374 | 0.86 | TTR (0.44) | TTRSMN1; SMN2NPC1RAB9AHDAC1 | |
| SCHEMBL8408950 | 0.84 | TTR (0.41) | TTRMAPK8SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8409285 | 0.84 | MAP3K7 (0.39) | TTRSMN1; SMN2POLBLMNAMEN1 | |
| SCHEMBL8409167 | 0.82 | EPHX2 (0.49) | TTRMAPK8SMN1; SMN2RAB9AEPHX2 | |
| SCHEMBL8407971 | 0.81 | NPC1 (0.35) | SMN1; SMN2NPC1RAB9APOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935900-A | BENZOTRIAZOLE COMPOUND, DIPHENYLSULFONE ELECTRON ACCEPTOR | OJL PAPER CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |