SCHEMBL8408804

SCHEMBL8408804

O=C(Nc1cc(F)cc(OCc2ccccc2)c1)C1CCOCC1

nearest known ligand 0.53

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
F10 P00742 18/20 0.53
F2 P00734 3/20 0.50
ELANE P08246 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8953741 0.82 KMT2A (0.50)
SCHEMBL8409250 0.81 ALOX5 (0.62) F10F2ELANE
Hydrochloric Acid SCHEMBL8411350 0.80 ALOX5 (0.61) F10F2ELANE
SCHEMBL332276 0.78 MAP4K4 (0.56)
SCHEMBL23795593 0.78 MAPK8 (0.60) F10
SCHEMBL8410878 0.76 MAP4K4 (0.52)
SCHEMBL8529894 0.75 RAB9A (0.70)
SCHEMBL8409075 0.75 F10 (0.72) F10
SCHEMBL1709134 0.74 PTGER1 (0.46) F10
SCHEMBL19015883 0.74 SMN1; SMN2 (0.50) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5883106-A 5-lipoxygenase inhibitors PFIZER INC. (US) 1999-03-16 US disclosed