Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8043991 | 0.94 | NPC1 (0.52) | NPC1RAB9APOLBTTRLMNA | |
| SCHEMBL8406921 | 0.92 | NPC1 (0.46) | NPC1RAB9APOLBTTRLMNA | |
| SCHEMBL8043981 | 0.88 | NPC1 (0.50) | NPC1RAB9APOLBTTRLMNA | |
| SCHEMBL8408950 | 0.88 | TTR (0.41) | NPC1RAB9ATTRLMNASMN1; SMN2 | |
| SCHEMBL8409160 | 0.87 | TTR (0.40) | NPC1RAB9ATTRLMNASMN1; SMN2 | |
| SCHEMBL8409167 | 0.87 | EPHX2 (0.49) | RAB9ATTRLMNASMN1; SMN2MAPT | |
| SCHEMBL8407973 | 0.86 | TTR (0.38) | NPC1RAB9APOLBTTRLMNA | |
| SCHEMBL9408799 | 0.84 | NPC1 (0.51) | NPC1RAB9APOLBLMNASMN1; SMN2 | |
| SCHEMBL9408778 | 0.84 | NPC1 (0.56) | NPC1RAB9APOLBLMNASMN1; SMN2 | |
| SCHEMBL9408745 | 0.83 | NPC1 (0.54) | NPC1RAB9APOLBLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935900-A | BENZOTRIAZOLE COMPOUND, DIPHENYLSULFONE ELECTRON ACCEPTOR | OJL PAPER CO., LTD. (JP) | 1999-08-10 | — | — | US | claimed |
| US-5935900-A | BENZOTRIAZOLE COMPOUND, DIPHENYLSULFONE ELECTRON ACCEPTOR | OJL PAPER CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |