Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 8/20 | 0.35 |
| ▸ | PGR | P06401 | 8/20 | 0.35 |
| ▸ | AR | P10275 | 7/20 | 0.35 |
| ▸ | STS | P08842 | 9/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8623329 | 0.79 | NR3C1 (0.51) | NR3C1PGRARCYP3A4ABCB11 | |
| SCHEMBL8624910 | 0.78 | NR3C1 (0.52) | NR3C1PGRARCYP3A4 | |
| SCHEMBL8407122 | 0.75 | PGR (0.40) | NR3C1PGRARCYP3A4 | |
| SCHEMBL9811526 | 0.74 | LMNA (0.30) | NR3C1PGRCYP3A4ABCB11 | |
| SCHEMBL8618776 | 0.73 | NR3C1 (0.43) | NR3C1PGRARCYP3A4 | |
| SCHEMBL8409143 | 0.73 | PGR (0.42) | NR3C1PGRARCYP3A4ABCB11 | |
| SCHEMBL8409403 | 0.71 | SRD5A2 (0.39) | NR3C1PGRAR | |
| SCHEMBL8409113 | 0.71 | SRD5A2 (0.39) | NR3C1PGRARCYP3A4 | |
| SCHEMBL9222376 | 0.69 | AR (0.39) | NR3C1PGRARCYP3A4ABCB11 | |
| SCHEMBL9222367 | 0.69 | AR (0.39) | NR3C1PGRARCYP3A4ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0565553-B1 | 6,7-MODIFIED 11$g(b)-ARYL-4-ESTRENES | SCHERING AG (DE) | 1999-07-21 | — | — | EP | disclosed |
| US-5843931-A | 6,7-modified 11β-aryl-4-oestrenes | SHERING AKTIENGESELLSCHAFT (DE) | 1998-12-01 | — | — | US | disclosed |