Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 5/20 | 0.42 |
| ▸ | PKLR | P30613 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29764209 | 1.00 | ACHE (0.44) | ACHEPKMPKLRTSHRALDH1A1 | |
| SCHEMBL532887 | 0.84 | PKM (0.50) | PKMPKLRALDH1A1HSD17B10TDP1 | |
| SCHEMBL1500713 | 0.84 | ALDH1A1 (0.40) | ACHETSHRALDH1A1HSD17B10TDP1 | |
| SCHEMBL17689094 | 0.81 | ACHE (0.46) | ACHEPKMPKLRTSHRALDH1A1 | |
| SCHEMBL7708264 | 0.79 | ACHE (0.44) | ACHEPKMPKLRTSHRALDH1A1 | |
| SCHEMBL13006836 | 0.79 | ACHE (0.44) | ACHEPKMPKLRTSHR | |
| SCHEMBL8412762 | 0.78 | ACHE (0.43) | ACHEPKMPKLRTSHRALDH1A1 | |
| SCHEMBL20149756 | 0.78 | ACHE (0.43) | ACHEPKMPKLRTSHRALDH1A1 | |
| SCHEMBL8412759 | 0.78 | ACHE (0.43) | ACHEPKMPKLRTSHRALDH1A1 | |
| SCHEMBL22187863 | 0.78 | ACHE (0.43) | ACHEPKMPKLRTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555555-B | Process for preparing 1,1' -disulfanediylbis (4-fluoro-2-methyl-5-nitrobenzene) | 拜耳公司 | 2024-03-01 | — | — | CN | disclosed |
| US-20230303509-A1 | SULFONAMIDO DERIVATIVES AS CYCLIN-DEPENDENT KINASE 2 INHIBITORS | NIKANG THERAPEUTICS, INC. | 2023-09-28 | — | — | US | disclosed |
| US-20220348538-A1 | PROCESS OF PREPARING 1,1'-DISULFANDIYLBIS(4-FLUORO-2-METHYL-5-NITROBENZOL) | BAYER AKTIENGESELLSCHAFT (DE) | 2022-11-03 | — | — | US | disclosed |
| EP-4045482-A1 | PROCESS OF PREPARING 1,1'-DISULFANDIYLBIS(4-FLUORO-2-METHYL-5-NITROBENZOL) | Bayer Aktiengesellschaft (DE) | 2022-08-24 | — | — | EP | disclosed |
| CN-114555555-A | Process for preparing 1, 1' -dithioalkanediyl bis (4-fluoro-2-methyl-5-nitrobenzene) | 拜耳公司 | 2022-05-27 | — | — | CN | disclosed |
| WO-2021074108-A1 | PROCESS OF PREPARING 1,1'-DISULFANDIYLBIS(4-FLUORO-2-METHYL-5-NITROBENZOL) | BAYER AKTIENGESELLSCHAFT (DE) | 2021-04-22 | — | — | WO | disclosed |
| WO-2007084319-A2 | DIARYL PIPERIDINES AS CB1 MODULATORS | SCHERING CORPORATION (US) | 2007-07-26 | — | — | WO | disclosed |
| CN-1339432-A | Extracting method for substituted phenyl compounds | ROHM & HAAS (US) | 2002-03-13 | — | — | CN | disclosed |
| CN-1070175-C | Process for the preparation of 2, 6-disubstituted benzenesulfonates or 2, 6-disubstituted benzenesulfonates further substituted in the 3-, 4-or 5-position | ROHM & HAAS (US) | 2001-08-29 | — | — | CN | disclosed |
| EP-0708087-B1 | Method for making a substituted benzene compound | ROHM & HAAS (US) | 1999-07-28 | — | — | EP | disclosed |
| CN-1174189-A | Process for preparing substituted benzene compounds | ROHM & HAAS (US) | 1998-02-25 | — | — | CN | disclosed |
| EP-0708087-A1 | Method for making a substituted benzene compound | ROHM AND HAAS COMPANY (US) | 1996-04-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303509-A1 | SULFONAMIDO DERIVATIVES AS CYCLIN-DEPENDENT KINASE 2 INHIBITORS | CDK2, CCNK, CCNI | ACHE 4844/4885PKM 707/4885PKLR 1071/4885 |
| US-20220348538-A1 | PROCESS OF PREPARING 1,1'-DISULFANDIYLBIS(4-FLUORO-2-METHYL-5-NITROBENZOL) | DDT, PFAS, DNPH1 | ACHE 30/4885PKM 1955/4885PKLR 3368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.