Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGMN | Q99538 | 2/20 | 0.52 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8407537 | 0.90 | ALDH1A1 (0.47) | LGMNMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL2654128 | 0.82 | MAPT (0.64) | LGMNPDK2MAPTALDH1A1KDM4E | |
| SCHEMBL8409141 | 0.81 | USP14 (0.46) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8718962 | 0.81 | CHRM4 (0.38) | KDM1A | |
| SCHEMBL8407515 | 0.78 | KDM1A (0.38) | KDM1A | |
| SCHEMBL8407178 | 0.76 | KDM1A (0.38) | KDM1A | |
| SCHEMBL7520148 | 0.76 | NOTUM (0.61) | LGMNPDK2MAPTALDH1A1KDM4E | |
| SCHEMBL21533588 | 0.70 | LGMN (0.69) | LGMNPDK2MAPTALDH1A1KDM4E | |
| SCHEMBL8884329 | 0.70 | KMT2A (0.66) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL23086805 | 0.70 | LGMN (0.62) | LGMNPDK2MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922763-A | ANTICOAGULANT; CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1999-07-13 | — | — | US | disclosed |
| US-5736559-A | CARDIOVASCULAR DISORDERS; RESPIRATORY SYSTEM DISORDERS | KARL THOMAE GMBH (DE) | 1998-04-07 | — | — | US | disclosed |