Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8409552 | 0.90 | LGMN (0.52) | ALDH1A1KDM4EMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL8409141 | 0.86 | USP14 (0.46) | ALDH1A1KDM4EMAPTL3MBTL1HPGD | |
| SCHEMBL8407178 | 0.81 | KDM1A (0.38) | — | |
| SCHEMBL8407515 | 0.78 | KDM1A (0.38) | — | |
| SCHEMBL8718962 | 0.76 | CHRM4 (0.38) | — | |
| SCHEMBL30589126 | 0.72 | DGAT2 (0.45) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL16128015 | 0.71 | ALDH1A1 (0.52) | ALDH1A1KDM4EMAPTSMN1; SMN2HPGD | |
| SCHEMBL8888134 | 0.71 | KMT2A (0.59) | ALDH1A1KDM4ESMN1; SMN2HPGDTSHR | |
| SCHEMBL5532095 | 0.71 | KDM4E (0.58) | ALDH1A1KDM4EMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL5538159 | 0.71 | KDM4E (0.58) | ALDH1A1KDM4EMAPTSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922763-A | ANTICOAGULANT; CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1999-07-13 | — | — | US | disclosed |
| US-5736559-A | CARDIOVASCULAR DISORDERS; RESPIRATORY SYSTEM DISORDERS | KARL THOMAE GMBH (DE) | 1998-04-07 | — | — | US | disclosed |