Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 9/20 | 0.38 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.37 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8407515 | 0.95 | KDM1A (0.38) | KDM1ADPP4 | |
| SCHEMBL8407178 | 0.90 | KDM1A (0.38) | KDM1ASLC16A3SLC16A1 | |
| SCHEMBL8407654 | 0.85 | HRH2 (0.41) | CHRM4KDM1AERAP1SIGMAR1 | |
| SCHEMBL8407652 | 0.82 | HRH2 (0.45) | CHRM4KDM1A | |
| SCHEMBL8409141 | 0.81 | USP14 (0.46) | KDM1A | |
| SCHEMBL8409552 | 0.81 | LGMN (0.52) | KDM1A | |
| SCHEMBL8409450 | 0.80 | KDM1A (0.40) | KDM1A | |
| SCHEMBL9170067 | 0.76 | SIGMAR1 (0.59) | CHRM4SIGMAR1 | |
| SCHEMBL8407537 | 0.76 | ALDH1A1 (0.47) | — | |
| SCHEMBL8409543 | 0.76 | KDM1A (0.41) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5736559-A | CARDIOVASCULAR DISORDERS; RESPIRATORY SYSTEM DISORDERS | KARL THOMAE GMBH (DE) | 1998-04-07 | — | — | US | disclosed |