Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SLC18A3 | Q16572 | 8/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8412317 | 0.94 | HSD11B1 (0.46) | HSD11B1ALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL8412316 | 0.85 | MEN1 (0.39) | ALDH1A1LMNADRD2GAAMAPK1 | |
| SCHEMBL8413553 | 0.84 | HSD11B1 (0.45) | HSD11B1ALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL6995219 | 0.75 | DRD2 (0.45) | HSD11B1ALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL8409854 | 0.75 | CYP2C19 (0.45) | HSD11B1ALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL8413133 | 0.75 | CYP2D6 (0.42) | HSD11B1ALDH1A1LMNAHTTSLC18A3 | |
| SCHEMBL8411972 | 0.71 | DRD2 (0.43) | ALDH1A1LMNADRD2HTR2AMAPK1 | |
| SCHEMBL8410575 | 0.71 | HTR7 (0.38) | LMNASMN1; SMN2HTTDRD2HTR2A | |
| SCHEMBL6994274 | 0.71 | DRD2 (0.46) | HSD11B1ALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL8411323 | 0.71 | CYP2C19 (0.46) | HSD11B1ALDH1A1LMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874429-A | ANTIISCHEMIC AGENTS; CEREBROVASCULAR DISORDERS; CIRCULATORY IDSORDERS | SUNTORY LIMITED (JP) | 1999-02-23 | — | — | US | disclosed |