Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8411966 | 0.91 | DRD2 (0.47) | DRD2HTR1AHTR7MAPTALDH1A1 | |
| SCHEMBL8410575 | 0.89 | HTR7 (0.38) | DRD2HTR1AHTR7MAPK1DRD4 | |
| SCHEMBL8519203 | 0.89 | DRD2 (0.39) | DRD2HTR1AHTR7MAPTDRD4 | |
| SCHEMBL8413058 | 0.89 | HTR7 (0.36) | DRD2HTR7MAPTDRD4ALDH1A1 | |
| SCHEMBL8412316 | 0.86 | MEN1 (0.39) | DRD2MAPTMAPK1DRD4ALDH1A1 | |
| SCHEMBL8411551 | 0.86 | MEN1 (0.39) | DRD2HTR1AHTR7MAPTDRD4 | |
| SCHEMBL8413390 | 0.85 | ADRB1 (0.37) | HTR7ALDH1A1 | |
| SCHEMBL8412315 | 0.83 | HTR7 (0.39) | DRD2HTR1AHTR7DRD4LMNA | |
| SCHEMBL8413215 | 0.83 | HTR1A (0.38) | DRD2HTR1AHTR7MAPTPKM | |
| SCHEMBL8410568 | 0.82 | HSD17B10 (0.38) | DRD2HTR1AHTR7ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874429-A | ANTIISCHEMIC AGENTS; CEREBROVASCULAR DISORDERS; CIRCULATORY IDSORDERS | SUNTORY LIMITED (JP) | 1999-02-23 | — | — | US | disclosed |