Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 6/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.46 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7849540 | 0.84 | AGTR1 (0.56) | AGTR1LTB4R2AGTR2 | |
| SCHEMBL8502142 | 0.76 | ACHE (0.54) | AGTR1LTB4R2AGTR2 | |
| SCHEMBL8325773 | 0.74 | AGTR1 (0.40) | AGTR1LTB4R2AGTR2 | |
| SCHEMBL7847610 | 0.74 | AGTR1 (0.50) | AGTR1AGTR2 | |
| SCHEMBL7850545 | 0.73 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL3906504 | 0.71 | BRS3 (0.70) | AGTR1LTB4R2AGTR2 | |
| SCHEMBL8325939 | 0.71 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL8327093 | 0.69 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL8327991 | 0.68 | AGTR1 (0.54) | AGTR1AGTR2 | |
| SCHEMBL11948564 | 0.67 | AGTR1 (0.53) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5985894-A | USEFUL IN THE TREATMENT OF CARDIOVASCULAR ILLNESSES | HOECHST MARION ROUSSEL (FR) | 1999-11-16 | — | — | US | disclosed |