Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | HTR7 | P34969 | 5/20 | 0.43 |
| ▸ | HTR1A | P08908 | 5/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8411972 | 0.91 | DRD2 (0.43) | DRD2HTR7HTR1AHTR2AALDH1A1 | |
| SCHEMBL8412306 | 0.88 | HTR7 (0.41) | DRD2HTR7POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL8519203 | 0.83 | DRD2 (0.39) | DRD2HTR7HTR1AHTR2AHTR6 | |
| SCHEMBL8413058 | 0.83 | HTR7 (0.36) | DRD2HTR7SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8412316 | 0.82 | MEN1 (0.39) | DRD2ALDH1A1MAPT | |
| SCHEMBL8411551 | 0.82 | MEN1 (0.39) | DRD2HTR7HTR1AHTR2AALDH1A1 | |
| SCHEMBL8413215 | 0.81 | HTR1A (0.38) | DRD2HTR7HTR1AHTR2AHTR6 | |
| SCHEMBL8410568 | 0.81 | HSD17B10 (0.38) | DRD2HTR7HTR1AHTR2AHTR6 | |
| SCHEMBL8413390 | 0.80 | ADRB1 (0.37) | HTR7ALDH1A1 | |
| SCHEMBL8413541 | 0.80 | HTR7 (0.39) | DRD2HTR7HTR1AHTR2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874429-A | ANTIISCHEMIC AGENTS; CEREBROVASCULAR DISORDERS; CIRCULATORY IDSORDERS | SUNTORY LIMITED (JP) | 1999-02-23 | — | — | US | disclosed |