Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.30 |
| ▸ | METAP1 | P53582 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19924408 | 0.86 | METAP2 (0.41) | METAP2METAP1 | |
| SCHEMBL16574584 | 0.84 | KIF11 (0.40) | METAP2METAP1 | |
| SCHEMBL24540526 | 0.82 | NOS1 (0.36) | METAP2METAP1 | |
| Hydrochloric Acid SCHEMBL2891851 | 0.82 | KIF11 (0.40) | METAP2METAP1 | |
| Hydrochloric Acid SCHEMBL2891848 | 0.82 | KIF11 (0.40) | METAP2METAP1 | |
| SCHEMBL15760500 | 0.81 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL18774172 | 0.81 | — | — | |
| SCHEMBL222325 | 0.77 | KIF11 (0.46) | — | |
| SCHEMBL15944812 | 0.77 | NOS2 (0.33) | — | |
| SCHEMBL12438549 | 0.77 | KIF11 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934260-A1 | N ALPHA-2-(4-NITROPHENYLSULFONYL)ETHOXYCARBONYL-AMINO ACIDS | Hyundai Pharm. Ind. Co., Ltd. (KR) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017638-A1 | Nα-2-(4-NITROPHENYLSULFONYL)ETHOXYCARBONYL-AMINO ACIDS | HYUNDAI PHARM. IND. CO., LTD. (KR) | 1998-04-30 | — | — | WO | disclosed |