Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8412287 | 1.00 | LMNA (0.44) | LMNAPOLBMEN1KMT2ATSHR | |
| SCHEMBL8412291 | 0.83 | LMNA (0.43) | LMNAPOLBMEN1KMT2ATSHR | |
| SCHEMBL2989889 | 0.78 | LMNA (0.53) | LMNAPOLBMEN1KMT2ATSHR | |
| SCHEMBL23542543 | 0.72 | POLB (0.47) | LMNAPOLBMEN1KMT2ATSHR | |
| SCHEMBL9300378 | 0.72 | LMNA (0.47) | LMNAPOLBMEN1KMT2ATSHR | |
| SCHEMBL15405045 | 0.72 | CA2 (0.43) | MEN1KMT2ATSHRGAACYP2C19 | |
| SCHEMBL30308140 | 0.71 | LMNA (0.46) | LMNAPOLBMEN1KMT2ATSHR | |
| SCHEMBL27944596 | 0.70 | SRC (0.52) | MEN1KMT2AGAACYP2C19SRC | |
| SCHEMBL8530450 | 0.69 | TSHR (0.48) | LMNAPOLBMEN1KMT2ATSHR | |
| SCHEMBL8530447 | 0.69 | TSHR (0.48) | LMNAPOLBMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948931-A | Preparation and use of α-(hydroxyimino) phosphonoacetic acids | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 1999-09-07 | — | — | US | disclosed |