Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 8/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 4/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8412376 | 0.94 | DRD2 (0.54) | DRD2SLC6A4ACHEHTR2AHTR1A | |
| SCHEMBL8412321 | 0.79 | DRD2 (0.36) | DRD2SLC6A4HTR2AHTR1AHTR7 | |
| SCHEMBL7000199 | 0.75 | ACHE (0.57) | DRD2SLC6A4ACHEHTR2AHTR1A | |
| SCHEMBL6996785 | 0.74 | ACHE (0.53) | DRD2SLC6A4ACHEHTR2AHTR1A | |
| SCHEMBL18432239 | 0.71 | DRD2 (0.82) | DRD2SLC6A4ACHEHTR2AHTR7 | |
| SCHEMBL8410575 | 0.70 | HTR7 (0.38) | DRD2SLC6A4HTR2AHTR1AHTR7 | |
| SCHEMBL8412306 | 0.70 | HTR7 (0.41) | DRD2HTR7 | |
| SCHEMBL7964524 | 0.69 | DRD2 (0.75) | DRD2SLC6A4ACHEHTR2AHTR1A | |
| SCHEMBL8412315 | 0.69 | HTR7 (0.39) | DRD2SLC6A4HTR2AHTR1AHTR7 | |
| SCHEMBL7360772 | 0.68 | DRD2 (0.53) | DRD2SLC6A4ACHEHTR2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874429-A | ANTIISCHEMIC AGENTS; CEREBROVASCULAR DISORDERS; CIRCULATORY IDSORDERS | SUNTORY LIMITED (JP) | 1999-02-23 | — | — | US | disclosed |