Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.33 |
| ▸ | ADAMTS5 | Q9UNA0 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8410575 | 0.90 | HTR7 (0.38) | HTR7SMN1; SMN2MEN1KMT2ADRD2 | |
| SCHEMBL8411966 | 0.88 | DRD2 (0.47) | HTR7ALDH1A1SMN1; SMN2POLBMAPT | |
| SCHEMBL8410568 | 0.85 | HSD17B10 (0.38) | HTR7ALDH1A1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL8412315 | 0.84 | HTR7 (0.39) | HTR7GRM2SMN1; SMN2DRD2 | |
| SCHEMBL8519203 | 0.84 | DRD2 (0.39) | HTR7ALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL8413058 | 0.84 | HTR7 (0.36) | HTR7ALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL8411972 | 0.83 | DRD2 (0.43) | HTR7ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL8413215 | 0.82 | HTR1A (0.38) | HTR7ALDH1A1KDM4EMAPTDRD2 | |
| SCHEMBL8412318 | 0.82 | HTR7 (0.38) | HTR7ALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL8413390 | 0.81 | ADRB1 (0.37) | HTR7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874429-A | ANTIISCHEMIC AGENTS; CEREBROVASCULAR DISORDERS; CIRCULATORY IDSORDERS | SUNTORY LIMITED (JP) | 1999-02-23 | — | — | US | disclosed |