SCHEMBL25836627

SCHEMBL25836627

COCCOCCOCCOc1c(I)cc(I)c(C)c1C

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
MAPT P10636 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
LMNA P02545 1/20 0.32
KDM4E B2RXH2 2/20 0.31
RECQL P46063 1/20 0.31
APP P05067 6/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22897402 0.91 ALDH1A1 (0.36) ALDH1A1KDM4E
SCHEMBL22906079 0.88 ALDH1A1 (0.33) ALDH1A1MAPTL3MBTL1LMNAKDM4E
SCHEMBL22897394 0.88 ALDH1A1 (0.33) ALDH1A1MAPTL3MBTL1LMNAKDM4E
SCHEMBL22897420 0.82 TDP1 (0.34) ALDH1A1MAPTL3MBTL1LMNAKDM4E
SCHEMBL26225285 0.80 MAPT (0.36) ALDH1A1MAPTL3MBTL1LMNAKDM4E
SCHEMBL26225284 0.80 MAPT (0.36) ALDH1A1MAPTL3MBTL1LMNAKDM4E
SCHEMBL22897398 0.80 ALDH1A1 (0.35) ALDH1A1KDM4E
SCHEMBL8412359 0.79 MAPT (0.32) ALDH1A1MAPTL3MBTL1LMNAKDM4E
SCHEMBL22897396 0.78 L3MBTL1 (0.37) ALDH1A1MAPTL3MBTL1LMNAKDM4E
SCHEMBL23268467 0.77 TDP1 (0.36) ALDH1A1MAPTL3MBTL1LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11744916-B2 Radiopaque polymers BIOCOMPATIBLES UK LIMITED 2023-09-05 US disclosed
US-11702498-B2 Radiopaque polymers BIOCOMPATIBLES UK LIMITED 2023-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11702498-B2 Radiopaque polymers OXER1, NR5A1, AQP1 ALDH1A1 3178/4885MAPT 4575/4885L3MBTL1 3906/4885
US-11744916-B2 Radiopaque polymers TPO, PGLS, IQGAP1 ALDH1A1 1464/4885MAPT 4511/4885L3MBTL1 2122/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.