SCHEMBL22897396

SCHEMBL22897396

COCCOCCOc1c(C)cc(I)cc1I

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.37
MAPT P10636 3/20 0.37
LMNA P02545 2/20 0.37
KDM4E B2RXH2 5/20 0.36
TDP1 Q9NUW8 3/20 0.33
HTR1A P08908 3/20 0.33
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
ALDH1A1 P00352 3/20 0.32
RECQL P46063 2/20 0.32
POLB P06746 1/20 0.32
HPGD P15428 1/20 0.32
ALOX12 P18054 1/20 0.32
MAPK1 P28482 1/20 0.32
HTR2A P28223 3/20 0.32
HTR7 P34969 3/20 0.32
ADRA1A P35348 2/20 0.32
HTR6 P50406 2/20 0.32
DRD2 P14416 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23791883 0.91 L3MBTL1 (0.39) L3MBTL1MAPTLMNAKDM4ETDP1
SCHEMBL25836738 0.80 MAPT (0.39) L3MBTL1MAPTLMNAKDM4ETDP1
SCHEMBL22897397 0.80 L3MBTL1 (0.37) L3MBTL1MAPTLMNAKDM4ETDP1
SCHEMBL8813207 0.80 TTR (0.35) L3MBTL1KDM4ETDP1MAPK1
SCHEMBL19880724 0.79 HTR1A (0.39) KDM4EHTR1AKMT2AALDH1A1RECQL
SCHEMBL26225285 0.79 MAPT (0.36) L3MBTL1MAPTLMNAKDM4ETDP1
SCHEMBL26225284 0.79 MAPT (0.36) L3MBTL1MAPTLMNAKDM4ETDP1
SCHEMBL22897455 0.78 ERN1 (0.40) L3MBTL1MAPTKDM4ETDP1MEN1
SCHEMBL29425548 0.78 ERN1 (0.40) L3MBTL1MAPTKDM4ETDP1MEN1
SCHEMBL25836627 0.78 ALDH1A1 (0.33) L3MBTL1MAPTLMNAKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230355833-A1 RADIOPAQUE POLYMERS BIOCOMPATIBLES UK LIMITED (GB) 2023-11-09 US disclosed
US-20230355833-A1 RADIOPAQUE POLYMERS BIOCOMPATIBLES UK LIMITED (GB) 2023-11-09 US disclosed
US-20230279172-A1 RADIOPAQUE POLYMERS Boston Scientific Medical Device Limited (IE) 2023-09-07 US disclosed
US-20230279172-A1 RADIOPAQUE POLYMERS Boston Scientific Medical Device Limited (IE) 2023-09-07 US disclosed
US-11744916-B2 Radiopaque polymers BIOCOMPATIBLES UK LIMITED 2023-09-05 US disclosed
US-11744916-B2 Radiopaque polymers BIOCOMPATIBLES UK LIMITED 2023-09-05 US disclosed
US-11702498-B2 Radiopaque polymers BIOCOMPATIBLES UK LIMITED 2023-07-18 US disclosed
US-11702498-B2 Radiopaque polymers BIOCOMPATIBLES UK LIMITED 2023-07-18 US disclosed
EP-4130105-A1 BIODEGRADABLE POLYMER Biocompatibles UK Limited (GB) 2023-02-08 EP disclosed
US-20210277162-A1 RADIOPAQUE POLYMERS Boston Scientific Medical Device Limited (IE) 2021-09-09 US disclosed
US-20210115171-A1 RADIOPAQUE POLYMERS Boston Scientific Medical Device Limited (IE) 2021-04-22 US disclosed
US-20210015963-A1 RADIOPAQUE POLYMERS BIOCOMPATIBLES UK LTD. (GB) 2021-01-21 US disclosed
WO-2021009734-A1 RADIOPAQUE POLYMERS BIOCOMPATIBLES UK LIMITED (GB) 2021-01-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210115171-A1 RADIOPAQUE POLYMERS C9, PARG, RAD50 L3MBTL1 751/4885MAPT 2112/4885LMNA 739/4885
US-20230279172-A1 RADIOPAQUE POLYMERS SSTR3, VHL, PLG L3MBTL1 1794/4885MAPT 3653/4885LMNA 2329/4885
US-11702498-B2 Radiopaque polymers OXER1, NR5A1, AQP1 L3MBTL1 3906/4885MAPT 4575/4885LMNA 3358/4885
US-20230355833-A1 RADIOPAQUE POLYMERS TPO, PGLS, IQGAP1 L3MBTL1 2122/4885MAPT 4511/4885LMNA 3452/4885
US-20210015963-A1 RADIOPAQUE POLYMERS TPO, PGLS, IQGAP1 L3MBTL1 2122/4885MAPT 4511/4885LMNA 3452/4885
US-11744916-B2 Radiopaque polymers TPO, PGLS, IQGAP1 L3MBTL1 2122/4885MAPT 4511/4885LMNA 3452/4885
US-20210277162-A1 RADIOPAQUE POLYMERS OXER1, NR5A1, AQP1 L3MBTL1 3960/4885MAPT 4605/4885LMNA 3337/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.