SCHEMBL8412626

SCHEMBL8412626

CCc1c(F)ccc(F)c1S(=O)(=O)Cl

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PSIP1 O75475 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8411115 0.78 HTT (0.31) PSIP1
SCHEMBL8411117 0.78 PSIP1 (0.31) PSIP1
SCHEMBL27141810 0.73 PSIP1 (0.37) PSIP1
SCHEMBL29907265 0.73 PSIP1 (0.37) PSIP1
SCHEMBL8854493 0.73
SCHEMBL8409413 0.73
SCHEMBL8412750 0.72 PKM (0.32)
SCHEMBL27450537 0.72
SCHEMBL31566482 0.72 TRPV4 (0.39)
SCHEMBL3523738 0.72 CA1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0708087-B1 Method for making a substituted benzene compound ROHM & HAAS (US) 1999-07-28 EP disclosed
EP-0708087-A1 Method for making a substituted benzene compound ROHM AND HAAS COMPANY (US) 1996-04-24 EP disclosed