Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 6/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8416012 | 0.94 | PTGER3 (0.35) | OPRD1PTGER3PTGER2 | |
| SCHEMBL8415372 | 0.91 | OPRD1 (0.39) | OPRD1KDM4C | |
| Hydrochloric Acid SCHEMBL8576436 | 0.90 | OPRD1 (0.39) | OPRD1KDM4C | |
| SCHEMBL8417042 | 0.85 | CTSG (0.35) | OPRD1PTGER2 | |
| Hydrochloric Acid SCHEMBL8571507 | 0.84 | CTSG (0.34) | OPRD1PTGER2 | |
| SCHEMBL8575501 | 0.77 | PTGER3 (0.35) | PTGER3PTGER2 | |
| SCHEMBL7273197 | 0.74 | OPRD1 (0.42) | OPRD1 | |
| SCHEMBL8573785 | 0.74 | FFAR4 (0.39) | OPRD1PTGER3PTGER2 | |
| Hydrochloric Acid SCHEMBL7420832 | 0.73 | OPRD1 (0.41) | OPRD1 | |
| SCHEMBL8520116 | 0.70 | L3MBTL1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880284-A | HAVING ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASES-INHIBITING EFFECTS | DR. KARL THOMAE GMBH (DE) | 1999-03-09 | — | — | US | disclosed |
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |
| US-5681841-A | PREVENTION CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1997-10-28 | — | — | US | disclosed |