Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.44 |
| ▸ | THRA | P10827 | 3/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8410990 | 0.96 | THRB (0.44) | THRBTHRAEPHX1EPHX2HRH3 | |
| SCHEMBL8413818 | 0.92 | KMT2A (0.42) | THRBTHRAEPHX2HRH3CYP1A2 | |
| SCHEMBL8413150 | 0.90 | KMT2A (0.41) | THRBTHRAEPHX1EPHX2HRH3 | |
| SCHEMBL8413202 | 0.84 | KMT2A (0.37) | EPHX2HPGDMEN1KMT2AFAAH | |
| SCHEMBL8410662 | 0.84 | FAAH (0.37) | EPHX2MEN1KMT2AFAAH | |
| SCHEMBL7907310 | 0.83 | THRB (0.46) | THRBTHRAEPHX1EPHX2HRH3 | |
| SCHEMBL7900609 | 0.81 | THRB (0.46) | THRBTHRAEPHX1EPHX2HRH3 | |
| SCHEMBL7900571 | 0.75 | KMT2A (0.42) | THRBTHRAEPHX1EPHX2HRH3 | |
| SCHEMBL7900560 | 0.74 | KMT2A (0.44) | THRBTHRAEPHX2HRH3CYP1A2 | |
| SCHEMBL29057152 | 0.74 | SPHK1 (0.54) | THRBTHRAEPHX1EPHX2SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0394417-B2 | SUPERTWIST LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 1999-08-04 | — | — | EP | disclosed |
| EP-0366985-B1 | Super twist liquid crystal display | MERCK PATENT GMBH (DE) | 1994-04-06 | — | — | EP | disclosed |
| EP-0366985-A1 | Super twist liquid crystal display | MERCK PATENT GmbH (DE) | 1990-05-09 | — | — | EP | disclosed |
| WO-1990004622-A1 | SUPERTWIST LIQUID CRYSTAL DISPLAY | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-05-03 | — | — | WO | disclosed |