Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 2/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7900609 | 0.94 | THRB (0.46) | KMT2AMEN1THRBLMNAMAPT | |
| SCHEMBL7900560 | 0.93 | KMT2A (0.44) | KMT2AMEN1THRBLMNAMAPT | |
| SCHEMBL7907310 | 0.90 | THRB (0.46) | KMT2AMEN1THRBLMNAMAPT | |
| SCHEMBL7910515 | 0.84 | FAAH (0.39) | KMT2AMEN1LMNAMAPTCETP | |
| SCHEMBL8413150 | 0.82 | KMT2A (0.41) | KMT2AMEN1THRBMAPTCYP1A2 | |
| SCHEMBL23496620 | 0.81 | THRB (0.52) | KMT2AMEN1THRBLMNAMAPT | |
| SCHEMBL7907462 | 0.80 | HTR2A (0.38) | KMT2AMEN1LMNAHPGDEPHX2 | |
| SCHEMBL8413818 | 0.77 | KMT2A (0.42) | KMT2AMEN1THRBMAPTCYP1A2 | |
| SCHEMBL8410990 | 0.77 | THRB (0.44) | KMT2AMEN1THRBCYP1A2CYP3A4 | |
| SCHEMBL8413623 | 0.75 | THRB (0.44) | KMT2AMEN1THRBCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6210760-B1 | SHORT SWITCHING TIMES AND GRADIENTS AND ANGULAR DEPENDENCIES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2001-04-03 | — | — | US | disclosed |
| US-5876626-A | HIGH SPEED SWITCHING | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-03-02 | — | — | US | disclosed |
| US-5387369-A | With specified mixture of components; short switching times | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-07 | — | — | US | disclosed |