Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 6/20 | 0.37 |
| ▸ | RXRB | P28702 | 6/20 | 0.37 |
| ▸ | RXRG | P48443 | 4/20 | 0.37 |
| ▸ | RBP1 | P09455 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8411313 | 0.91 | POLB (0.42) | POLBPKMMEN1KMT2AALDH1A1 | |
| SCHEMBL8411148 | 0.83 | RXRA (0.39) | POLBKDM4ELMNARXRARXRB | |
| SCHEMBL8412765 | 0.83 | RXRA (0.37) | POLBKDM4ELMNARXRARXRB | |
| SCHEMBL8414354 | 0.81 | RXRA (0.39) | POLBKDM4ELMNARXRARXRB | |
| SCHEMBL8413617 | 0.80 | HDAC1 (0.38) | POLBKDM4ELMNARXRARXRB | |
| SCHEMBL8414356 | 0.78 | RXRB (0.38) | POLBKDM4ELMNARXRARXRB | |
| SCHEMBL8413481 | 0.77 | PPARG (0.36) | LMNARXRARXRBRXRGPPARG | |
| SCHEMBL8410982 | 0.77 | RXRA (0.37) | POLBKDM4ELMNARXRARXRB | |
| SCHEMBL8410755 | 0.75 | TBXAS1 (0.35) | ALDH1A1NPSR1RXRARXRBRXRG | |
| SCHEMBL8410745 | 0.73 | PTGIR (0.51) | POLBKDM4ELMNARXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962439-A | CARDIOVASCULAR DISORDER | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5849919-A | Fused benzeneoxyacetic acid derivatives which have PGI2 receptor anonist activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |