Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 5/20 | 0.39 |
| ▸ | HTR7 | P34969 | 3/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8412349 | 0.91 | L3MBTL1 (0.42) | DRD2HTR7DRD4KDM4ELMNA | |
| SCHEMBL8413371 | 0.81 | TYR (0.41) | TYRDRD2KDM4ELMNAGAA | |
| SCHEMBL8412330 | 0.81 | TYR (0.41) | TYRDRD2HTR7KDM4ELMNA | |
| SCHEMBL8413784 | 0.78 | TYR (0.40) | TYRDRD2HTR7KDM4ELMNA | |
| SCHEMBL8412311 | 0.77 | HSD11B1 (0.47) | DRD2LMNA | |
| SCHEMBL8413103 | 0.76 | L3MBTL1 (0.41) | DRD2HTR7DRD4KDM4ELMNA | |
| SCHEMBL7109759 | 0.75 | DRD2 (0.46) | DRD2HTR7DRD4 | |
| SCHEMBL8412328 | 0.74 | NPC1 (0.41) | DRD2HTR7DRD4LMNAMAPT | |
| SCHEMBL8413577 | 0.74 | MAPT (0.40) | TYRKDM4ELMNAGAAMAPT | |
| SCHEMBL8410749 | 0.73 | POLB (0.35) | DRD2DRD4KDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874429-A | ANTIISCHEMIC AGENTS; CEREBROVASCULAR DISORDERS; CIRCULATORY IDSORDERS | SUNTORY LIMITED (JP) | 1999-02-23 | — | — | US | disclosed |