Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8413531 | 0.92 | L3MBTL1 (0.37) | MAPTLMNAKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL8413815 | 0.87 | HTR7 (0.39) | MAPTKMT2ANPSR1HSD17B10KDM4E | |
| SCHEMBL8413130 | 0.85 | L3MBTL1 (0.38) | MAPTLMNAKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL8413732 | 0.84 | MEN1 (0.39) | MAPTGAAKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL8413058 | 0.84 | HTR7 (0.36) | TYRMAPTGAALMNAALDH1A1 | |
| SCHEMBL8411972 | 0.79 | DRD2 (0.43) | MAPTLMNAKMT2AALDH1A1HTR7 | |
| SCHEMBL8413553 | 0.79 | HSD11B1 (0.45) | LMNAKMT2AALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL8413538 | 0.78 | L3MBTL1 (0.38) | MAPTLMNAKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL8412330 | 0.78 | TYR (0.41) | TYRMAPTGAALMNAKMT2A | |
| SCHEMBL8413893 | 0.78 | TYR (0.42) | TYRMAPTGAALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874429-A | ANTIISCHEMIC AGENTS; CEREBROVASCULAR DISORDERS; CIRCULATORY IDSORDERS | SUNTORY LIMITED (JP) | 1999-02-23 | — | — | US | disclosed |