Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ME1 | P48163 | 7/20 | 0.37 |
| ▸ | ME2 | P23368 | 6/20 | 0.37 |
| ▸ | ME3 | Q16798 | 6/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESRRG | P62508 | 2/20 | 0.36 |
| ▸ | ESRRB | O95718 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8413134 | 0.90 | TP53 (0.39) | MAPTLMNANPC1ALDH1A1 | |
| SCHEMBL8412330 | 0.84 | TYR (0.41) | MAPTKDM4EGAALMNATYR | |
| SCHEMBL8410491 | 0.77 | TP53 (0.40) | MAPTLMNAMAPK1NPC1USP2 | |
| SCHEMBL8413001 | 0.75 | L3MBTL1 (0.41) | MAPTKDM4ELMNAALDH1A1KMT2A | |
| SCHEMBL8413893 | 0.74 | TYR (0.42) | MAPTKDM4EGAALMNATYR | |
| SCHEMBL8413058 | 0.73 | HTR7 (0.36) | MAPTKDM4EGAALMNATYR | |
| SCHEMBL8413371 | 0.73 | TYR (0.41) | MAPTKDM4EGAALMNATYR | |
| SCHEMBL8413784 | 0.72 | TYR (0.40) | MAPTKDM4EGAALMNATYR | |
| SCHEMBL6997213 | 0.70 | DRD2 (0.43) | ESR1ESRRG | |
| SCHEMBL8413423 | 0.70 | HTR7 (0.43) | KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874429-A | ANTIISCHEMIC AGENTS; CEREBROVASCULAR DISORDERS; CIRCULATORY IDSORDERS | SUNTORY LIMITED (JP) | 1999-02-23 | — | — | US | disclosed |