Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5808831 | 0.85 | ALDH1A1 (0.42) | ALDH1A1LMNASMN1; SMN2HTR2AHTR2B | |
| SCHEMBL842632 | 0.83 | TLR7 (0.42) | ALDH1A1TP53LMNAHTR2AHTR2B | |
| SCHEMBL843383 | 0.81 | ALDH1A1 (0.32) | ALDH1A1TP53LMNASMN1; SMN2CASP1 | |
| SCHEMBL4056414 | 0.80 | ALDH1A1 (0.41) | ALDH1A1TP53LMNASMN1; SMN2KDM4E | |
| SCHEMBL191697 | 0.78 | LMNA (0.39) | ALDH1A1TP53LMNASMN1; SMN2HTR2A | |
| SCHEMBL192522 | 0.76 | TSHR (0.42) | ALDH1A1TP53LMNASMN1; SMN2HTR2A | |
| SCHEMBL1490884 | 0.75 | TP53 (0.36) | ALDH1A1TP53LMNASMN1; SMN2HTR2A | |
| SCHEMBL5808535 | 0.73 | TLR7 (0.55) | LMNAHTR2AHTR2BPOLBHRH2 | |
| SCHEMBL3355085 | 0.73 | TLR7 (0.45) | KDM4EPDE4DTLR7GLA | |
| SCHEMBL842450 | 0.70 | TLR7 (0.49) | KDM4ENUDT1TLR7GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143270-B2 | 2-amino 1H-in-imidazo ring systems and methods | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-03-27 | — | — | US | disclosed |