Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL646908 | 0.84 | IDO1 (0.38) | IDO1RIPK1 | |
| SCHEMBL1567091 | 0.84 | IDO1 (0.52) | IDO1TAAR1ALDH1A1RIPK1PARP10 | |
| SCHEMBL14008209 | 0.77 | TAAR1 (0.43) | TAAR1TSHRKMT2A | |
| SCHEMBL1146014 | 0.76 | IDO1 (0.61) | IDO1TAAR1ALDH1A1PARP10MAPT | |
| SCHEMBL13603792 | 0.75 | IDO1 (0.55) | IDO1TAAR1ALDH1A1MAPTHTT | |
| SCHEMBL13050671 | 0.75 | ALDH1A1 (0.45) | IDO1ALDH1A1MAPTTSHRHTT | |
| SCHEMBL18240037 | 0.75 | TAAR1 (0.42) | TAAR1TSHRKMT2A | |
| Lithium SCHEMBL18240038 | 0.75 | TAAR1 (0.42) | TAAR1TSHRKMT2A | |
| SCHEMBL18185026 | 0.75 | FDPS (0.38) | IDO1ALDH1A1TSHRSMN1; SMN2CA12 | |
| SCHEMBL8576825 | 0.75 | IDO1 (0.55) | IDO1TAAR1ALDH1A1RIPK1PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143069-B2 | useful for selective measurement of hypochlorite ion; does not react with hydrogen peroxide which is a weakly reactive oxygen species, and does not induce increase of fluorescence with hydroxyl radical or peroxynitrite which are reactive oxygen species having high activity | THE UNIVERSITY OF TOKYO (JP) | 2012-03-27 | — | — | US | disclosed |
| US-20090317914-A1 | FLUORESCENT PROBE | THE UNIVERSITY OF TOKYO (JP) | 2009-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090317914-A1 | FLUORESCENT PROBE | H1-10, H1-0, NHERF1 | IDO1 2633/4885TAAR1 793/4885ALDH1A1 1940/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.